PMS (also known as PMT) encompasses as many as 150 different symptoms, although no woman experiences them all.

When one considers how common the symptoms of PMS are in "technologically advanced" cultures (somewhere between 60% and 80% of all menstruating women between the ages of 20 and 50 experience regular symptoms of PMS) the conclusion might be drawn that women (and their partners) are simply destined to suffer.

However - because there are numerous cultures among whom this condition is essentially non-existent and unknown - diet, stress and xenoestrogens (foreign oestrogens), often introduced in the form of contraceptives, are all major contributors to this disorder. PMS symptoms generally include all or some combination of:

Irritability, Frustration & Anger
Chronic Fatigue
Depression/Loss of Esteem
Mood Swings
Panic Attacks
Food Cravings
Loss of Libido
Irregular Periods/Bleeding
Bloating/Water Retention
Weight Gain
Muscle/Joint Pain
Foggy Thinking
Vertigo
Acute Headaches/Migraines
Breast Swelling & Tenderness


As if the above symptoms are not enough, the secondary consequences can include impaired work ability and strained interpersonal relationships.

Traditional Treatments

Traditional treatments have included tranquilizers, diuretics, dietary changes, thyroid supplements, herbs, vitamins, exercise and acupuncture. While these may provide some easing of symptoms, the underlying causes remain.

Successful Treatments

Dr. Joel T. Hargrove of Vanderbilt University Medical Center, USA has seen a 90% success rate in treating PMT with oral doses of natural progesterone. An even higher rate of success has been reported by Dr. John R. Lee using Transdermal Natural Progesterone Cream in his practice for more than 17 years. Dr. Lee is a retired gynaecologist who has been a pioneer of Natural Progesterone Therapy.

The difference between the methods of application is that oral progesterone requires 5-8 times the daily dose to obtain the same results as Transdermal Progesterone Cream. Approximately 80% of oral progesterone is intercepted by the liver and conjugated by glucuronic acid for excretion in the bile. Additionally, oral progesterone will produce a sharp rise in serum progesterone levels followed by a rapid drop in serum levels within several hours.

In thirty years of clinical practice Dr. Lee has observed the consistent benefits and safety of natural progesterone therapy. He made this statement:

"Though not completely understood, PMS most commonly represents an individual reaction to oestrogen dominance, secondary to relative progesterone deficiency. Appropriate treatment requires correction of this hormone imbalance and the most effective technique, at present, for achieving this is supplemental Transdermal Natural Progesterone Cream"

After reviewing the Serenity Natural Progesterone Cream formula Dr Lee stated "That's Perfect". *
* This information is for general interest only. Every woman is unique. Your results may vary.