PMS encompasses a huge range of symptoms - and potential treatments. But some treatments are more successful than others.
Serenity Cream
Natural PMS Relief
Bioidentical progesterone cream for the relief of cramping, insomnia, mood swings and other symptoms of PMS
Natural Progesterone Cream
Premenstrual syndrome (PMS) has a wide variety of signs and symptoms. It's estimated that as many as 3 of every 4 menstruating women have experienced some form of premenstrual syndrome.
Bioidentical progesterone can help alleviate PMS symptoms by counteracting the effects of excess oestrogen, which fluctuates during the menstrual cycle.
Bioidentical progesterone can help alleviate PMS symptoms by counteracting the effects of excess oestrogen, which fluctuates during the menstrual cycle.
Effective PMS Symptom Relief
Including cramping, bloating, insomnia, mood swings, tender breasts, food cravings, fatigue, irritability and depression.*
Natural, Bioidentical Hormones
The active ingredient in Wellsprings Serenity is natural progesterone which is bioidentical to your body’s own progesterone. *
Tried and Tested
Wellsprings Serenity has been helping relieve the symptoms of PMS for thousands of women since 1997. *
How Serenity Works
Oestrogen and progesterone are the two dominant reproductive hormones in women. Both are necessary and work in concert with each other. However, a combination of factors including extended use of birth control, processed foods and environmental toxins can cause the increasingly common condition of oestrogen dominance.
The bioidentical progesterone in Serenity cream redresses this balance, producing a calming effect on the body that can positively impact many PMS symptoms.
The bioidentical progesterone in Serenity cream redresses this balance, producing a calming effect on the body that can positively impact many PMS symptoms.
- Mood swings: Progesterone can help regulate neurotransmitters, such as serotonin and GABA, which play a role in mood stability.
- Irritability: Progesterone's calming effect can help reduce irritability and promote emotional well-being.
- Bloating: Progesterone can help balance fluid levels and reduce water retention, which can contribute to bloating.
- Breast tenderness: Some studies suggest that progesterone may reduce breast tenderness associated with PMS.
- Cramps: Progesterone can help relax the uterine muscles, which may help reduce menstrual cramps.
IMPORTANT: Serenity cream is NOT recommended if you are using the pill, implant or coil for contraception unless you take responsibility for additional contraceptive precautions. It can be used alongside these products if you only use them to help regulate heavy bleeding.
What doctors say about natural progesterone cream...
Dame Dr Shirley Bond
DCmdrSOStj MB BS LRCP MRCS FFARCS
DCmdrSOStj MB BS LRCP MRCS FFARCS
"I had never been keen to give my patients traditional HRT and now I had a safe product to use to help them deal with their problems and balance their hormones."
Dr B Peatfield
DCmdrSOStj MB BS LRCP MRCS
DCmdrSOStj MB BS LRCP MRCS
"I have been using natural progesterone cream for some years now... both my patients and I have, without exception, been delighted with its efficacy."
What our customers say about Serenity natural progesterone cream...
JH, Northamptonshire
After so many attempts at trying to improve my PMS, Serenity has been the only proper relief I have had. *
MP, Oxfordshire
"Since using the cream, I can honestly say that my menstrual health and general outlook on life have taken a huge turn for the better." *
BM, West Midlands
"Thank you for such a wonderful product... almost all of my symptoms have abated this month." *
* Please note that our customer reviews are individual experiences. Your results may vary.
Why Bioidentical Progesterone?
Unlike some HRT products, Wellsprings Serenity replenishes your body with progesterone that is bioidentical to that produced in the body naturally, restoring hormone balance and relieving the symptoms of oestrogen dominance and PMS.
Why a Cream?
In pill form bioidentical progesterone is filtered out by the liver, reducing effectiveness and potentially causing a number of side effects. Skin application is known to be most effective for hormone absorption and Serenity is a hyper-liposomal cream which optimises progesterone uptake and maximises symptom relief.
60ml jar lasts 2+ months 100ml bottle lasts 4+ months
60ml jar lasts 2+ months
100ml bottle lasts 4+ months
100ml bottle lasts 4+ months
A Premium Progesterone Cream
Wellsprings Serenity is a gentle, fragrance free, natural progesterone cream with an advanced liposomal formula that optimises absorption.
Certified Bioidentical Progesterone Content
2.34% Natural Progesterone
Each 60ml (2.1oz) jar of Serenity contains 1,404mg of bioidentical USP Pharmaceutical grade Natural Progesterone extracted from plant saponins.
Advanced Liposomal Formula
Enhanced Absorption
Serenity’s advanced liposomal formula optimises progesterone absorption while keeping skin looking healthy and moisturised in areas where applied.
Hypo-Allergenic
All natural ingredients
Free from common allergens.
Fragrance Free
For discreet application
Serenity is fragrance free so as not to interfere with other scented products you may be using.
Animal Friendly
No animal testing
Serenity is not tested on animals in any way and no animal by-products are used in its formulation.
Ingredients
Ingredients
Deionized Water, Caprylic/Capric Triglyceride, Glycerin, Aloe Barbadensis Leaf Juice, Progesterone, Phenoxyethanol, Caprylyl Glycol, Sorbic Acid, Cetyl Alcohol, Glyceryl Stearate, Isopropyl Myristate, Stearic Acid, Sodium, Hyaluronate, Sodium PCA, Methyl Glucose Sesquistearate, Aminomethyl Propanol, Carbomer, Tocopheryl Acetate, Grapefruit Seed Extract, PEG-20 Methyl Glucose Sesquistearate, Xanthan Gum.
60ml jar lasts 2+ months 100ml bottle lasts 4+ months
60ml jar lasts 2+ months
100ml bottle lasts 4+ months
100ml bottle lasts 4+ months
A dose of Wellsprings Serenity cream should be applied morning and evening to thin tissue areas of the body. It is important to gently rub the cream into a different area each time.
Each recommended dose of cream is 1/8th of a teaspoon (0.5ml). This amount is the size of a garden pea.
Each recommended dose of cream is 1/8th of a teaspoon (0.5ml). This amount is the size of a garden pea.
Usage Schedule *
Usage Schedule *
Serenity cream should be applied twice daily, starting 14 days after the first day of your bleed. So for the first week of your bleed, and the week following, do not apply the cream. Repeat this cycle each month.
Usage Overview
Each dose of Serenity contains 12mg of bioidentical progesterone, so one application in the morning and one in the evening will constitute a dosage of 24mg per day.
If symptoms are severe you may use a double dose mornings and evenings, but all women are different and dosage should be assessed and modified by each individual through their own experience over a period of time.
Each 60ml jar contains around 120 pea-sized doses, so a jar will last around 4 months for those on the pre-menopausal regime and around 10 weeks for those on the 24 day menopausal regime.
Our 100ml pump bottle contains around 200 pea-sized doses, so a bottle will last around 7 months for those on the pre-menopausal regime and around 4 months for those on the 24 day menopausal regime.*
If symptoms are severe you may use a double dose mornings and evenings, but all women are different and dosage should be assessed and modified by each individual through their own experience over a period of time.
Each 60ml jar contains around 120 pea-sized doses, so a jar will last around 4 months for those on the pre-menopausal regime and around 10 weeks for those on the 24 day menopausal regime.
Our 100ml pump bottle contains around 200 pea-sized doses, so a bottle will last around 7 months for those on the pre-menopausal regime and around 4 months for those on the 24 day menopausal regime.*
Applying Cream
Serenity should be applied to thin tissue areas of the body, rotating between different areas each day.
The best application areas are: the face, neck, inside of the upper arms, lower back and inner thighs.
The best application areas are: the face, neck, inside of the upper arms, lower back and inner thighs.
Top Tip
Top Tips
How to measure a single dose
Simply dab the underside of your little finger halfway to the nail if using a jar, or gently press the pump if using our pump bottle. The amount should be about the size of a garden pea.
Top Tip
Quick Relief
For a more instant effect (for migraine headaches for example) it has been found that massaging a little extra cream into the areas of thin skin (inner wrists, temples and behind the ears) may give relief.
* Every woman is unique. Your results may vary
Why hasn't my doctor prescribed natural progesterone?
Natural progesterone has in fact been prescribed since the 1930s and a growing number of doctors are now recommending it.
The major pharmaceutical companies market HRT treatments that contain artificial hormones that they can patent and are profitable. The resources of these companies has enabled them to position them as the standard prescription for menopause symptoms and other conditions of hormonal imbalance despite increasing reports of their side effects. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
What is Oestrogen Dominance?
The major pharmaceutical companies market HRT treatments that contain artificial hormones that they can patent and are profitable. The resources of these companies has enabled them to position them as the standard prescription for menopause symptoms and other conditions of hormonal imbalance despite increasing reports of their side effects. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
What is Oestrogen Dominance?
What are the conditions that natural progesterone can benefit?
Natural progesterone is most commonly used to treat both short and long term symptoms associated with Oestrogen Dominance.
During menopause these symptoms include:
- Hot flushes
- Night Sweats
- Brain fog
- Mood swings & depression
- Water retention
- Breast swelling and pain
- Heavy or irregular periods
- Uterine fibroids
- Weight gain, particularly around hips and thighs
One of the prime long term conditions associated with oestrogen dominance is osteoporosis. Natural Progesterone can be an effective treatment for this condition. *
Relevant articles:
What is Oestrogen Dominance?
Natural Progesterone
Osteoporosis & Natural Progesterone
During menopause these symptoms include:
- Hot flushes
- Night Sweats
- Brain fog
- Mood swings & depression
- Water retention
- Breast swelling and pain
- Heavy or irregular periods
- Uterine fibroids
- Weight gain, particularly around hips and thighs
One of the prime long term conditions associated with oestrogen dominance is osteoporosis. Natural Progesterone can be an effective treatment for this condition. *
Relevant articles:
What is Oestrogen Dominance?
Natural Progesterone
Osteoporosis & Natural Progesterone
What is natural progesterone?
Natural progesterone, also known as bioidentical progesterone, is 100% the same as the progesterone hormone produced naturally in the body. As such it is treated by the body the same way and can perform all the functions of the body's own progesterone.
Prescribed since the 1930s, it is used to treat menopause related symptoms and other conditions associated with hormone imbalance.
It is important to recognise the difference between natural progesterone and the artificial progesterones (progestins) used in common HRT treatments. While in some ways progestins perform in the same manner as natural progesterone they are in fact chemically different and thus not treated by the body the same way. This is believed to be behind the reported side effects of common HRT treatments. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
What is Oestrogen Dominance?
Prescribed since the 1930s, it is used to treat menopause related symptoms and other conditions associated with hormone imbalance.
It is important to recognise the difference between natural progesterone and the artificial progesterones (progestins) used in common HRT treatments. While in some ways progestins perform in the same manner as natural progesterone they are in fact chemically different and thus not treated by the body the same way. This is believed to be behind the reported side effects of common HRT treatments. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
What is Oestrogen Dominance?
Why does Serenity contain just progesterone and no oestrogen?
Specialists have identified that a deficiency in progesterone in relation to oestrogen is at the root of most women's hormonal complaints.
Doctors such as Dr John R Lee, who prescribed natural progesterone for 30 years and wrote extensively about its benefits, demonstrated that supplementing progesterone alone, in its natural form, is what most sufferers require in order for health and wellbeing to be restored. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
What is Oestrogen Dominance?
Doctors such as Dr John R Lee, who prescribed natural progesterone for 30 years and wrote extensively about its benefits, demonstrated that supplementing progesterone alone, in its natural form, is what most sufferers require in order for health and wellbeing to be restored. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
What is Oestrogen Dominance?
Are there any side effects associated with natural progesterone?
There have been no reported side effects associated with natural progesterone since it was first prescribed, over 60 years ago. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
How can a cream get natural progesterone into my body?
'Transdermal application' is the method of delivering substances into the body through the skin. It is used in products such as nicotine patches and pain-killing gels.
When taken orally, natural progesterone gets removed almost entirely by the liver. When applied in cream form over 90% of the progesterone content is absorbed. *
Relevant articles:
Transdermal Creams - How they work and why
Doctors and Natural Progesterone
When taken orally, natural progesterone gets removed almost entirely by the liver. When applied in cream form over 90% of the progesterone content is absorbed. *
Relevant articles:
Transdermal Creams - How they work and why
Doctors and Natural Progesterone
What is the difference between Serenity and conventional HRT treatments?
Most conventional HRT treatments prescribed to treat progesterone deficiency employ chemically modified, artificial progesterones known as progestins. While performing in some ways like natural progesterone, these substances are alien to the body and not treated the same way. This is believed to be behind the reported side effects of conventional HRT treatments. *
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
Relevant articles:
Natural Progesterone
Doctors and Natural Progesterone
Each 60ml jar contains around 120 pea-sized doses, so a 60ml jar will last around four months for those on the pre-menopausal regime and around ten weeks for those on the 24 day menopausal regime. Our 100ml pump bottle contains around 200 pea-sized doses, so a bottle will last around seven months for those on the pre-menopausal regime and around four months for those on the 24 day menopausal regime.
Wellsprings Serenity has a natural progesterone content of 1,404mg per 60ml (2.1oz) jar, which is equivalent to 2.34%.
Is there medical research behind the claims for natural progesterone?
Can I use Wellsprings creams alongside the contraceptive coil or pill?
If you're using these just to help with heavy bleeding then simultaneous use with your cream is fine. However, if you're using them for contraception, then no we CANNOT recommend it, unless you also take additional precautions.
The coil and pill both contain synthetic progestins which compete with the same receptor sites in the body as the natural progesterone in our creams to make both less effective.
The coil and pill both contain synthetic progestins which compete with the same receptor sites in the body as the natural progesterone in our creams to make both less effective.
* Every woman is unique. Your results may vary
60ml jar lasts 2+ months 100ml bottle lasts 4+ months
60ml jar lasts 2+ months
100ml bottle lasts 4+ months
100ml bottle lasts 4+ months
Based on the foundation of enhancing natural progesterone, this 3 step plan could be a complete solution for PMS problems
Hear what doctors have to say about natural progesterone and its benefits
Based on the foundation of enhancing natural progesterone, this 3 step plan could be a complete solution for PMS problems
Over 35? Then you could still be at risk of PMS and those symptoms you thought you had left behind long ago
PMS responds very well to progesterone, but there are a few more things that can enhance your response and make a real difference
What exactly is Premenstrual Syndrome and how can you recognise its symptoms?
The causes and effects of PMS can be more complex and interrelated than mainstream medicine allows for.
In the third part of his series on PMS, Dr Coope looks at the treatments available for symptoms relief
In the fourth and final part of his series on PMS Dr Coope discusses the deeper and more gentle holistic approaches to symptoms relief
All information given on this site is for general interest only. Every woman is unique. Your results may vary.
Serenity Cream Questions
* Please note that our customer reviews are individual experiences. Your results may vary.
